Instructions for Authors

Manuscript submission

Manuscripts must be submitted to the co-Editors in Chief (bteb@amgtranscend.org / review@btebulletin.com) in full compliance with the “Biomaterials and Tissue Engineering Bulletin”  policy regarding the originality of the papers. “Biomaterials and Tissue Engineering Bulletin” does not wish to receive any paper that has already been reported in parts or contains already published text, data or results. The manuscript should be submitted by one of the authors, who has the responsibility of getting the consent of all coauthors and the approval of the particular institution from which the papers are submitted.

It is recommended for the authors to submit manuscripts as electronic Word (.doc, .docx) files, to save time for the reviewing process. Each submitted paper will be examined scientifically by at least two reviewers and evaluated ethically by one or two editors. Authors are welcome to submit highly original papers, in accordance with ethical standards.

Concurrent submissions

To ensure a wide range of author diversity, authors will be limited to have no more than three manuscripts under review at any time. If there are any authors that already have three manuscripts under review, they may send others manuscripts for consideration only when the review process is complete for at least one of the already submitted manuscripts.

Ethical compliance

If a submitted manuscript reports preclinical (in vitro or/and in vivo trials) experiments or/and clinical studies, it should contain a statement which certify that the necessary experiments were performed in optimal conditions regarding the wellbeing of the subjected organisms and that the experiments were conducted with animal or/and human ethics committee approval.

If the submitted manuscripts imply human stem cells experiments, the papers are accepted only if the ultimate goal of the in vitro tests harness the therapeutic potential of these cell lines. The therapeutic potential associated with the use of human stem cells follows different research paths: cell therapy (in order to replace a defective tissue), indirect therapeutic development (in order to control the endogenous tissue neo-formation and regeneration) and development and improvement of conventional therapies(in order to develop and revolutionize classical pharmaceutical therapies).

When the submitted manuscript reports experiments on animals, authors should indicate which guideline/law regarding the care and use of laboratory animals was followed.The submitted papers that imply the use of laboratory animals must be conducted in full compliance with the effective legislation, regulation and administrative directives regarding the protection of live vertebrate animals used for scientific or other experimental purposes. The experimental activities which require the use of laboratory animals must be conducted in full compliance with the “3R Principle”: refinement(the selected animals must be similar in terms of species and quality; researchers and auxiliary staff must have the required qualifications, must treat animals with kindnessand take necessary measures to avoid or reduce the animals’ discomfort or pain; the procedures that cause animals pain or long suffering must be performed under sedation, analgesia or anesthesia), reduction (animal experiments are allowed only after an accurate analysis of the relevance towards human physiology and scientific progress; the required experiments must involve a minimum number of laboratory animals in order to obtain accurate scientific and statistical results; the research animals must have the best life conditions) and replacement(as much as possible, it is encouraged to use alternative methods for research studies, in order to achieve the experimental purpose without using live animals experiments).The submitted papers containing in vivo tests are accepted for publication only if the use of laboratory animals in experimental activities is performed according to the international standards regarding the protection of animals used for scientific purposes, established in 2010/63/EU Directive.

When the submitted manuscript reports studies on human subjects, identifying details about the patient should be omitted if they are not essential (except for the clinical cases in which these details are essential for scientific purposes and the patient gives written informed consent for publication; when informed consent has been obtained it should be indicated in the submitted article). All the submitted papers which require experimental activities and results regarding human subject research experiments must be conducted in full compliance with the ethical standards of local or regional ethics committees and with the Declaration of Helsinki 1975, revised Hong Kong 1989.

Manuscript style

All manuscripts should be written using our template and should be submitted in English.

  • Manuscript title:The title of the manuscript should not have more than 30 words and should not contain abbreviations;
  • Author information: This section of manuscript must include complete names and affiliation of all authors and contact details of corresponding author (telephone, fax and e-mail address);
  • Abstract: The abstract should be a completely self-contained and citation-free summary of the whole manuscript, which should briefly present the topic, state the scope of the paper, indicate significant data and point out major conclusions, and also it should not exceed 200 words; following the abstract, a list of keywords (3-8) and abbreviations should be included;
  • Introduction: A succinct introduction is required to provide a clear background to the subject, its significance and its previous impact (considering thus relevant literature) and the proposed solution or approach for solving the current problem;
  • Materials and methods: This part should contain complete, correct and detailed information regarding employed materials, interventions and analytical methods, in order to ensure the reproducibility of all experiments;
  • Results and discussion: This section should provide complete details on the experimental results, as well as emphasize the impact of the achieved results;
  • Conclusions: This part should clearly explain the relevant conclusions of the submitted paper, as well as the current impact and potential applications;
  • Acknowledgements: All acknowledgements (if any) should be brief and placed at the end of the paper after the references;
  • References: References should include only articles that are published or in press. For references to in press articles, please confirm with the cited journal that the article is in fact accepted and in press and include a DOI number and online publication date. Unpublished data, submitted manuscripts, abstracts, and personal communications should be cited within the text only. Personal communication should be documented by a letter of permission. Submitted articles should be cited as unpublished data, data not shown, or personal communication.

Please use the style shown below for references. Note that “et al.” should only be used after ten authors.

Article in journal:
Guzun, A.S., Stroescu, M., Jinga, S.I., Voicu, G., Grumezescu, A.M., and Holban, A.M. (2014). Plackett–Burman experimental design for bacterial cellulose–silica composites synthesis. Materials Science and Engineering: C 42, 280-288.

Holban, A.M., Grumezescu, V., Grumezescu, A.M., Vasile, B.Ş., Truşcă, R., Cristescu, R., Socol, G., and Iordache, F. (2014). Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique. Beilstein Journal of Nanotechnology 5, 872-880.

Chapter in a book:
Cipriano, A.F., and Liu, H. (2013). Biomaterials and nano-scale features for ligament regeneration. In Nanomaterials in Tissue Engineering, A.K. Gaharwar, S. Sant, M.J. Hancock, and S.A. Hacking, eds. (Woodhead Publishing), pp. 334-360.

Dang, T.T., Nikkhah, M., Memic, A., and Khademhosseini, A. (2014). Chapter 19 – Polymeric Biomaterials for Implantable Prostheses. In Natural and Synthetic Biomedical Polymers, S.G.K.T.L. Deng, ed. (Oxford: Elsevier), pp. 309-331.

Tang, X., Thankappan, S.K., Lee, P., Fard, S.E., Harmon, M.D., Tran, K., and Yu, X. (2014). Chapter 21 – Polymeric Biomaterials in Tissue Engineering and Regenerative Medicine. In Natural and Synthetic Biomedical Polymers, S.G.K.T.L. Deng, ed. (Oxford: Elsevier), pp. 351-371

An entire book:
Cowan, W.M., Jessell, T.M., and Zipursky, S.L. (1997). Molecular and Cellular Approaches to Neural Development (New York: Oxford University Press).

  • Abbreviations: Avoid using abbreviations in the title and abstract; terms that are used frequently within the text may be abbreviated and must be defined at their first use;
  • Units of measurement: All measurements should be presented by using International System of Units (S.I.);
  • Figures:The recommended file formats for photographic images are bitmap formats (Photoshop, GIFF, JPEG, TIFF) and all the figures should be included in the manuscript file, not separately; it is also recommended to begin each legend with a title and include a concise description of the figure, as well as to use Arabic numerals to designate figures and upper case letters for their components (if any);
  • Tables: Tables should be consequently identified by using Arabic numerals, followed by a brief explanatory title, and they should be referred to in the text;
  • Conflict of interest: We require that our authors disclose any financial or other conflict of interest that may influence the results or their interpretation in their submitted manuscript.